Molecule of the Month
January 2019

Fluorescent RNA Aptamers

RNA aptamers are being engineered to track molecules inside living cells

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Health Focus: Antimicrobial Resistance

Antibiotics have saved countless lives, but pathogens are quickly finding ways to survive antibiotic treatment. Antibiotic-resistant bacteria are predicted to become the leading cause of death worldwide. They take many approaches: pumping antibiotics out of their cells, altering the molecular machinery that the antibiotics target, and attacking the antibiotics directly. Atomic structures publicly available in the PDB are revealing the details of drug resistance and providing new ways to combat it. Use the predisclose to learn about protein structures related to antibiotic action and resistance.


2019 Video Challenge for High School Students

(215) 756-2200

Tell a 2 minutes story that combines Structural Biology and Medicine and submit your video between January 15 and April 23, 2019.

Quick Links

The Challenge | (303) 535-4166 | 706-626-3758 | 2019 Judges

843-418-2691
Learn: Materials for Exploration
Learn about the relationship between protein structure and function.
Teach: Curricula
The 775-335-7554 provide authentic, hands-on teaching materials, individual and group activities and assessment suggestions.
Education Corner: Using PDB Resources
Creating Accessible Tools for Molecular Visualization Instruction By Kristen Procko and the BioMolViz Group
Geis Digital Archive
Irving Geis (1908-1997) was a gifted artist who helped illuminate the field of structural biology with his iconic images. The Geis Digital Archive features many of his illustrations in the context of their molecular structures.

Images used with permission from the Howard Hughes Medical Institute (www.hhmi.org). All rights reserved.

Deoxyribonucleic Acid (DNA)

Lysozyme

Tomato Bushy Stunt Virus (TBSV)

Hemoglobin S

Myoglobin

Hemoglobin

Cytochrome c

Immunoglobulin G (IgG)

Cytochrome c (unbound)

DPG-Hemoglobin Complex

Transfer Ribonucleic Acid (tRNA)

TATA-Binding Protein (TBP)

Hemoglobin

Myoglobin Fold

Lac Repressor

DNA

Z-DNA

Oxyhemoglobin

Ribonuclease S

Deoxyhemoglobin

Trypsin

Induced Lac Repressor

Collagen

Carboxypeptidase A

Myohemerythrin

A-DNA

B-DNA

Crambin

Lysozyme

Intermolecular Contacts in Hemoglobin S